Drivable short-term, but fix now to avoid damage.
This code means the engine computer found an electrical fault in the wiring or control circuit for the fuel injector on cylinder 8. The usual culprits are a failing injector, damaged wiring or connectors, or a problem in the circuit driving it. Fixing it typically means testing the injector and wiring and replacing whatever part has failed, and it's often resolved without tearing into the engine.
$150 – $500
Varies by vehicle and root cause.
Short trips are usually fine, but it's not something to ignore. A dead or weak cylinder can damage your catalytic converter and leave you stranded, so get it looked at soon. If the engine shakes badly or loses power, stop and have it towed.
Expect roughly $150 to $500. Wiring or connector repairs are cheaper, while replacing the cylinder 8 injector with labor lands at the upper end of that range.
It can be serious. The injector circuit fault usually leads to misfires that can damage emissions parts and worsen fuel economy if left alone. It's best to address it promptly.
Quite possibly. A misfiring cylinder dumps unburned fuel into the exhaust, which raises emissions and can trip an inspection failure. Fixing the injector usually clears the problem.